南京大学医学院-欧洲杯下单平台

药学进展青年编委

《bme&phs》编委

江苏省生物医学工程学会理事会理事

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4.qingsong ye; deyuan zheng a; kaiyuan chen; jinhui wu*. research progress in oxygen carrier design and application. molecular pharmaceutics 

5.gong tong; jinhui wu*. synthetic engineered bacteria for cancer therapy. drug delivery

6.yang liu, yuchen wang, chao wang, tiejun dong, haiheng xu, yunfei guo, xiaozhi zhao*, yiqiao hu*, jinhui wu*, hijacking self-assembly to establish intracellular functional nanoparticles. adv sci. 2022 sep 8;e2203027

3.zhuo feng, yuchen wang, haiheng xu, yunfei guo, wen xia, chenxuan zhao, xiaozhi zhao, jinhui wu*, recent advances in bacterial therapeutics based on sense and response. acta pharmaceutica sinica b, 2022

4.xianghui li, haoran wang, zhiyan li, dandan li, xiaofeng lu, shichao ai, yuxiang dong, song liu*, jinhui wu*, wenxian guan*, oxygen tank for synergistic hypoxia relief to enhance mitochondria-targeted photodynamic therapy, biomaterials research, 2022, september 22: 47.

5.haiheng xu, yiqiao hu and jinhui wu*, flagellated bacterial porter for in situ tumor vaccine. mirobial cell. 2022 aug 24;9(9):158-161

6.jialong xu, wenjing zai, qingsong ye, qingqing zhang, wenqian yi and jinhui wu*. a nitroreductase responsive and photoactivated fluorescent probe for dual-controlled tumor hypoxia imaging. rsc adv., 2022, 12, 23796-23800

7.yuchen wang, chenxuan zhao, yang liu, chao wang, haojie jiang, yiqiao hu, jinhui wu, recent advances of tumor therapy based on the cd47-sirpα axis. molecular pharmaceutics 19 (5), 1273-1293.

8.lihong gu, feng zhang, jinhui wu*, yuzheng zhuge，nanotechnology in drug delivery for liver fibrosis. front mol biosci. 2022 jan 11;8:804396

9.huanhuan chen, yunfei guo, zhewei zhang, wenxuan mao, chenying shen, wei xiong, yingfang yao, xiaozhi zhao, yiqiao hu, zhigang zou, and jinhui wu*. symbiotic algae–bacteria dressing for producing hydrogen to accelerate diabetic wound healing. nano letter, 2021, 20 december

10.haoran wang, honghui liu, yunfei guo, wenjing zai, xianghui li, wei xiong, xiaozhi zhao, yingfang yao, yiqiao hu, zhigang zou, jinhui wu*. photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect. bioactive materials, 2021, 28 october 2021

11.wenjing zai, lin kang, tiejun dong, haoran wang, lining yin, shaoju gan, wenjia lai, yibing ding, yiqiao hu, jinhui wu*.e. coli membrane vesicles as catalase carrier for long term tumor hypoxia relief to enhance radiotherapy. acs nano, 2021, 15, 9, 15381–15394.

systemic immune responses to irradiated tumours via the transport of antigens to the tumour periphery by injected flagellate bacteria. nature biomedical engineering. 2021. （highlight in nature biomedical engineering）

13.lining yin, yuye huang, chao wang, hong dong, yibing ding, bin huang, jinhui wu*, development of a novel and stability indicating rp-hplc-uv method for simultaneous analysis of carbetocin and ten impurities in carbetocin injection products.2021, 84, 967–978.

14.chao wang, zhaoyi sun, chenxuan zhao, zhewei zhang, haoran wang, yang liu, yunfei guo, bingtao zhang, lihong gu, yue yu, yiqiao hu, jinhui wu*. maintaining manganese in tumor to activate cgas-sting pathway evokes a robust abscopal anti-tumor effect. journal of controlled release, 2021, 331,480

15.haoran wang, yunfei guo, shaoju gan, honghui liu, qian chen, ahu yuan, yiqiao hu, jinhui wu*. photosynthetic microorganisms‐based biophotothermal therapy with enhanced immune response. small, 2021，17, 2007734

16.haoran wang, yunfei guo，chaowang，xing jiang，honghui liu，ahu yuan，jing yan，yiqiao hu，jinhui wu*. light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia. biomaterials, 269, 120621

17.huanhuan chen， yuhao cheng, jingrun tian, peizheng yang, xuerao zhang, yunhao chen, yiqiao hu*, jinhui wu*. dissolved oxygen from microalgae-gel patch promotes chronic wound healing in diabetes. science advance, 2020, 6(20), eaba4311

18.qing li, yuye huang, yu zhang, huayuan cui, lining yin, ahu yuan, yiqiao hu, jinhui wu*. a novel hplc method for analysis of atosiban and its five related substances in atosiban acetate injection. journal of pharmaceutical and biomedical analysis 177, 112808

19.zhaoyi sun, chengjun song, chao wang, yiqiao hu*, jinhui wu*, hydrogel-based controlled drug delivery for cancer treatment: a review. -391.

20.zaigang zhou, baoli zhang, wenjing zai, lin kang, ahu yuan, yiqiao hu*, jinhui wu*, perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of t cells and boosts immunotherapy. pnas, 2019 may 29. pii: 201901987.

21.peng yu，xiaoxue han，lining yin，kangyu hui，yunfei guo，ahu yuan，yiqiao hu*，jinhui wu*, artificial red blood cells constructed by replacing heme with perfluorodecalin for hypoxia‐induced radioresistance. 

22.wenguang wang, yuhao cheng, peng yu, haoran wang, yue zhang, haiheng xu, qingsong ye, ahu yuan, yiqiao hu, jinhui wu*, perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. nature communications. 2019, 10:1580.

23.zaigang zhou, baoli zhang, haoran wang, ahu yuan*, yiqiao hu*, jinhui wu*, two-stage oxygen delivery for enhanced radiotherapy by perfluorocarbon nanoparticles. theranostics. 2018,8(18),4898-4911[详情]

24.zaigang zhou, baoli zhang, shushan wang, wenjing zai, ahu yuan*, yiqiao hu*, jinhui wu*, perfluorocarbon nanoparticles mediated platelet blocking disrupt vascular barriers to improve the efficacy of oxygen-sensitive antitumor drugs. small. 2018,14, 1801694

25.lingtong meng, yali cheng, xiaoning tong, shaoju gan, yawen ding, yu zhang, chao wang, lei xu, yishen zhu, jinhui wu*, yiqiao hu*, and ahu yuan*，tumor oxygenation and hypoxia inducible factor-1 functional inhibition via a reactive oxygen species responsive nanoplatform for enhancing radiation therapy and abscopal effects. acs nano. 2018,12(8):8308-8322.

26.xuefeng qiu，kai cao, tingsheng lin, wei chen, ahu yuan, jinhui wu*, yiqiao hu, hongqian guo*, drug delivery system based on dendritic nanoparticles for enhancement of intravesical instillation. int j nanomedicine. 2017, 10(12), 7365-7374

27.huibo lian, jinhui wu*, yiqiao hu, hongqian guo*, self-assembled albumin nanoparticles for combination therapy in prostate cancer. int j nanomedicine. 2017, 24(12), 7777-7787

28.xiaolei tang, yuanyuan cao, jiaqian yu, runjie shi, yuye huang, jinhui wu* and yiqiao hu* development and validation of hplc methods for the determination of propranolol hydrochloride and hydrochlorothiazide related substances in combination tablets. international journal of drug development and research, 2017, 9(x):1-6;

29.hao ren, jiaqi liu, yuqin li, haoran wang, sizhan ge, ahu yuan, yiqiao hu, jinhui wu*, oxygen self-enriched nanoparticles functionalized with erythrocyte membranes for long circulation and enhanced phototherapy, acta biomaterialia, 2017, 59(x), 269-282;

30.xing jiang, kaikai wang, zaigang zhou, yifan zhang, huizi sha, qiuping xu, jie wu, juan wang, jinhui wu, yiqiao hu, baorui liu, erythrocyte membrane nanoparticles improve the intestinal absorption of paclitaxel. biochemical and biophysical research communications; 2017,488(2),322-328;

31.xiaolei tang, yuhao cheng, shiting huang, ahu yuan, yiqiao hu*, jinhui wu*, overcome the limitation of hypoxia against photodynamic therapy to treat cancer cells by using perfluorocarbon nanodroplet for photosensitizer delivery. biochemical and biophysical research communications; 2017,487(3),483-487;

32.yifan zhang, yuncai guan, sizhan ge, jinhui wu*, yiqiao hu*; light-responsive co2 bubble-generating polymeric micelles for tumor cell ablation; medicinal chemical communications; 2017,8(x),405-407;[详情]

; 2017,9(4),3463-3473;

34.ahu yuan，wei huan，xiang liu, zhicheng zhang，yifan zhang，jinhui wu*，yiqiao hu*; nir light-activated drug release for synergetic chemo-photothermal therapy; molecular pharmaceutics; 2017,14 (1), 242–251;

35.tingsheng lin, xiaozhi zhao, yifang zhang, huibo lian, junlong zhuang, qin zhang, wei chen, wei wang, suhan guo, jinhui wu *, yiqiao hu *, hongqian guo *; floating hydrogel with self-generating micro-bubbles for intravesical instillation; materials; 2016,9,1005;

36.linfeng xu, xufeng qiu, yifan zhang, kai cao, xiaozhi zhao, jinhui wu*, yiqiao hu*, hongqian guo*; liposome encapsulated perfluorohexane enhances radiotherapy in mice without additional oxygen supply; j transl med; 2016,14:268;

37.yifan zhang，lingyi he，jie wu, kaikai wang,weimin dai, ahu yuan, jinhui wu*, yiqiao hu*; switchable pdt for reducing skin photosensitization by a nir dye inducing self-assembled and photo-disassembled nanoparticles; biomaterials; 2016,107:23-32;

38.kaikai wang, yifan zhang, juan wang, ahu yuan, minjie sun, jinhui wu*, yiqiao hu*; self-assembled ir780-loaded transferrin nanoparticles as an imaging, targeting and pdt/ptt agent for cancer therapy; sci rep; 2016 jun 6,6:27421;

39.xuefeng qiu, linfeng xu, yanting zhang, ahu yuan, kaikai wang, xiaozhi zhao, jinhui wu*, hongqian guo*, yiqiao hu*; photothermal ablation of in situ renal tumor by peg-ir780-c13 micelles and near-infrared irradiation; molecular pharmaceutics; 2016 mar 7,13(3):829-38;

40.kaikai wang, ahu yuan, juan wang, jinhui wu*, yiqiao hu*; one-step self-assembling method to prepare dual-functional transferrin nanoparticles for antitumor drug delivery; j pharm sci; 2016 mar,-76;featured article most original and most significant scientific findings

41.kaikai wang , juan wang, wenwen hu, yifan zhang, feng zhi, zaigang zhou, jinhui wu*, and yiqiao hu*; acid denaturation inducing self-assembly of curcumin-loaded hemoglobin nanoparticles; materials; 2015, 8(12), 8701-8713;

42.yuhao cheng, hao cheng, chenxiao jiang, xuefeng qiu, kaikai wang, wei huan, ahu yuan, jinhui wu*, yiqiao hu*; perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy; ;

43.guanchen zhu, yifan zhang, kaikai wang, xiaozhi zhao, huibo lian, wei wang, haoran wang, jinhui wu*, yiqiao hu* and hongqian guo*; visualized intravesical floating hydrogel encapsulating vaporized perfluoropentane for controlled drug release; drug delivery; 2015 oct 30:1-7;

44.yifan zhang, youwei zhu, na zhao, jinhui wu*, yiqiao hu*; application of isothermal titration calorimeter for screening bitterness-suppressing molecules of quinine; food chemistry; 2016,190(1), 1007–1012;

45.xiaolei tang, guijun wang, runjie shi, ke jiang, lingtong meng, hao ren, jinhui wu*, and yiqiao hu*; enhanced tolerance and antitumor efficacy by docetaxel-loaded albumin nanoparticles; drug delivery; 2015,26:1-11;

46.zhengjie meng, lingtong meng, kaikai wang, jing li, xiaoli cao, jinhui wu* yiqiao hu*; enhanced hepatic targeting, biodistribution and antifibrotic efficacy of tanshinone iia loaded globin nanoparticles; european journal of pharmaceutical sciences; 2015,73:35-43;

47.xuefeng qiu, yanting zhang, xiaozhi zhao, shiwei zhang, jinhui wu*, hongqian guo*, yiqiao hu*; enhancement of endothelial differentiation of adipose derived mesenchymal stem cells by a three-dimensional culture system of microwell; biomaterials; 2015, 53,600–608;

48.ahu yuan, xuefeng qiu, xiaolei tang, wei liu, jinhui wu*, yiqiao hu*; self-assembled peg-ir-780-c13 micelle as a targeting, safe and highly-effective photothermal agent for in vivo imaging and cancer therapy; biomaterials; 2015 may,51:184-93;

49.ahu yuan, xiaolei tang, xufeng qiu, jiang ke, jinhui wu*, yiqiao hu*; activatable photodynamic destruction of cancer cells by nir dye/photosensitizer loaded liposomes; chem commun; 2015, 51, 3340-3342;

50.zheyi hu, zaigang zhou, yahui hu, jinhui wu*, yunman li, wenlong huang; hz08 reverse p-glycoprotein mediated multidrug resistance in vitro and in vivo; plos one; 2015,feb17, 10(2):e0116886;

51.chenxiao jiang, hao cheng, ahu yuan, xiaolei tang, jinhui wu*, yiqiao hu*; hydrophobic ir780 encapsulated in biodegradable human serum albumin nanoparticles for photothermal and photodynamic therapy; ;

52.zhengjie meng, xiaoyan yang, die hu, kaikai wang, feng zhi, xi chen, guangming gong, jinhui wu*, yiqiao hu*; replacing heme with paclitaxel to prepare drug loaded globin nanoassembles for cd163 targeting; j pharm sci; 2015 mar,104(3):1045-55;

53.zaigang zhou, xiaolei tang, jinhui wu*, yiqiao hu*; l-1416, a novel mdr reversing agent with reduced calcium antagonism; pharmacol rep; 2014 dec,66(6):1140-7;

54.tingsheng lin, yifan zhang, jinhui wu*, xiaozhi zhao, huibo lian, wei wang, hongqian guo, yiqiao hu*; a floating hydrogel system capable of generating co2 bubbles to diminish urinary obstruction after intravesical instillation; pharmaceutical research; october 2014, 31( 10),2655-2663;

55.lili zhao, ying gao, guoxiang gu, jinhui wu*, zhining fan, hong dong and yiqiao hu*;rational design of drug-eluting stents via electrospray and in vivoevaluation of preventing oesophageal stricture; rsc adv; 2014,4, 16885-16892;

56.tingsheng lin , jinhui wu*, xiaozhi zhao, huibo lian, ahu yuan, xiaolei tang, yiqiao hu*, hongqian guo; in situ floating hydrogel for intravesical delivery of adriamycin without blocking urinary tract; journal of pharmaceutical sciences; 2014 mar,103(3):927-36;

57.dawei ding, xiaolei tang, jinhui wu*, ahu yuan, chenchen song, xiang zhang, qian qiao, jing pan, yiqiao hu*; novel self-assembly endows human serum albumin nanoparticles with an enhanced antitumor efficacy as abraxane; aaps pharmscitech; 2014 feb,15(1):213-22;

58.jinhui wu, chenchen song, chenxiao jiang, xin shen, qian qiao, yiqiao hu*; nucleolin targeting as1411 modified protein nanoparticle for antitumor drugs delivery; molecular pharmaceutics; 2013 oct 7,10(10):3555-63;

59.sai zhao, jinhui wu*; hypoxia inducible factor stabilization as a novel strategy to treat anemia; current medicinal chemistry; 2013, 20(21):2697-711;

60.ahu yuan, jinhui wu*, chenchen song, xiaolei tang, yiqiao hu*; a novel self-assembly albumin nanocarrier for reducing doxorubicin mediated cardiotoxicity; journal of pharmaceutical sciences; 2013,102(5),1626-1635;

61.ahu yuan, jinhui wu*, xiaolei tang, lili zhao, feng xu, yiqiao hu*; application of near infrared dyes for tumor imaging, photothermal and photodynamic therapies; journal of pharmaceutical sciences; 2013 jan,102(1):6-28;

62.yan xu, feng zhi, guangming xu, xiaolei tang, sheng lu, jinhui wu*，yiqiao hu*; overcoming multidrug resistance in vitro and in vivo by a novel p-glycoprotein inhibitor 1416; bioscience reports; 2012, 32(6):559-566;

63.xiang zhang, lili zhao, jinhui wu*, hong dong, yiqiao hu*; current advances in vehicles for brain gene delivery; current gene therapy; 2012,12(5):423-436;

64.guangming gong, yan xu, yuanyuan zhou, zhengjie meng, guoyan ren, yang zhao, xiang zhang, jinhui wu*, yiqiao hu*; molecular switch for the assembly of lipophilic drug incorporated plasma protein nanoparticles and in vivo image; biomacromolecules; 2012, 9,13(1):23-8;

65.zhaobin chen, jinhui wu*, feng xu, yiqiao hu*; recent advances in bitter evaluationmethods; analytical methods; 2012,4, 599-608;

66.lin wu, jinhui wu*, yuanyuan zhou, xiaolei tang, yiqiao hu*; enhanced antitumor efficacy and decreased side effects of platinum by tirapazamine-transferrin conjugate; international journal of pharmaceutics; 2012, jul 15,431(1-2):190-6;

67.lili zhao, jinhui wu*, he zhou, ahu yuan, xiang zhang, feng xu, yiqiao hu*; local gene delivery for cancer therapy; current gene therapy; 2011,11(5)423-442;

68.jinhui wu, ian wheeldon，yuqi guo, tingli lu, yiqiao hu, ali khademhosseni; a sandwiched microarray platform for benchtop cell-based high throughput screening; biomaterials; 2011,32 (3) 841-848;

69.jinhui wu, dawei ding, guoyan ren, xiangyang xu, xiaojin yin, yiqiao hu*; sustained delivery of endostatin improves the efficacy of therapy in lewis lung cancer model; journal of controlled release; 2009, 134 (2) 91-97;

70.jinhui wu, lin wu, xiaoqiang xu, xiangyang xu, xiaojin yin, yingjie chen, yiqiao hu*; microspheres made by w/o/o emulsion method with reduced initial burst for long-term delivery of endostar, a novel recombinant human endostatin; journal of pharmaceutical sciences; 2009, 98(6):2051-8;

71.jinhui wu, qiujuan wang, jiyuan guo, zheyi hu, zhiyong yin, jinyi xu, xiaoming wu; characterization of angiotensin ii antagonism displayed by ib, a novel nonpeptide angiotensin at1 receptor antagonist; european journal of pharmacology; 2008, 589(1-3):220-4;

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