王守宇博士
教授
电话:邮箱:sywang@nju.edu.cn 地址:汉口路22号研究方向:
肿瘤表观遗传 教育经历: 1999.09-2004.07 南京医科大学获得学士学位 2004.09-2009.07 南京医科大学获得博士学位
2009.09-2014.07 南京医科大学 讲师 2013.08-2016.04 美国ut md anderson肿瘤中心 博士后 2014.07-2018.12 南京医科大学 副教授,硕士生导师 2019.01-至今 南京大学 教授,博士生导师 1、江苏省环境诱变剂学会理事; 2、中国医防整合联盟理事; 3、中国抗癌协会肿瘤标志专业委员会非编码rna 与肿瘤研究专家委员会委员; 4、中国抗癌协会会员; 5、中国毒理学会会员; 6、中国细胞生物学会会员 (1) qiang wang#, chen chen#, xiao xu#, chuanjun shu#, changchang cao#, zhangding wang, yao fu, lei xu, kaiyue xu, jiawen xu, anliang xia, bo wang, guifang xu, xiaoping zou, ruibao su, wei kang, yuanchao xue*, ran mo*, beicheng sun*, shouyu wang*. apaf1-binding long non-coding rna promotes tumor growth and multidrug resistance in gastric cancer by blocking apoptosome assembly. advanced science. 2022 aug 17;e2201889. (2) anliang xia#, wenwen yuan#, qiang wang#, jianbo xu#, yayun gu, liansheng zhang, chen chen, zhangding wang, di wu, qifeng he, weiwei yu, fei wang, cailin xue, yan zhang, guojian bao, xuewen tao, siyuan liu, shouyu wang*, zhibin hu*, beicheng sun*. the cancer-testis lncrna lnc-cthcc promotes hepatocellular carcinogenesis by binding hnrnp k and activating yap1 transcription. nature cancer. 2022 feb;3(2):203-218. (3) zhangding wang#, yao fu#, anliang xia#, chen chen, jiamu qu, guifang xu, xiaoping zou*, qiang wang*, shouyu wang*. prognostic and predictive role of a metabolic rate-limiting enzyme signature in hepatocellular carcinoma. cell proliferation. 2021 oct;54(10):e13117. (4) chen chen#, ningmei shen#, yali chen, pinping jiang, wei sun, qiang wang, zhangding wang, yi jiang, wenjun cheng*, shilong fu*, shouyu wang*. lnccclm inhibits lymphatic metastasis of cervical cancer by promoting stau1-mediated igf-1 mrna degradation. cancer letters. 2021 july;518:169–179. (5) qiang wang#, chen chen#, qingqing ding#, yan zhao, zhangding wang, junjie chen, zerun jiang, yan zhang, guifang xu, jingjing zhang, jianwei zhou, beicheng sun*, xiaoping zou*, shouyu wang*. mettl3-mediated m6a modification of hdgf mrna promotes gastric cancer progression and has prognostic significance. gut. 2020 jul;69(7):1193-1205. (6) qiang wang#, wei geng#, huimin guo#, zhangding wang, kaiyue xu, chen chen, shouyu wang*. emerging role of rna methyltransferase mettl3 in gastrointestinal cancer. journal of hematology&oncology. 2020 may;13(1):57. (7) zhangding wang#, qiang wang#, guifang xu#, na meng#, xinli huang, zerun jiang, chen chen, yan zhang, junjie chen, aiping li, nan li, xiaoping zou, jianwei zhou, qingqing ding*, shouyu wang*. the long noncoding rna cral reverses cisplatin resistance via the mir-505/cyld/akt axis in human gastric cancer cells. rna biology. 2020 nov;17(11):1576-1589. (8) qingsong hu#, chunlai li#, shouyu wang#, yajuan li#, bo wen, yanyan zhang, ke liang, jun yao, youqiong ye, heidi hsiao, tina k. nguyen, peter k. park, sergey d. egranov, david h. hawke, jeffrey r. marks, leng han, mien-chie hung, bing zhang, chunru lin*, liuqing yang*, lncrnas-directed pten enzymatic switch governs epithelial-mesenchymal transition. cell research. 2019 apr;29 (4):286-304. (9) jie wu#, zerun jiang#, chen chen#, qingsong hu, ziyi fu, junjie chen, zhangding wang, qiang wang, aiping li, jeffrey r. marks, changying guo, yun chen, jianwei zhou, liuqing yang, chunru lin, shouyu wang*, circirak3 sponges mir-3607 to facilitate breast cancer metastasis. cancer letters. 2018 aug;430:179-192. (10) shouyu wang#, ke liang#, qingsong hu#, jian song, yuedong yang, jun yao, selanere mangala, chunlai li, wenhao yang, peter k. park, david h. hawke, jianwei zhou, yan zhou, weiya xia, mien-chie hung, jeffery r. marks, gary e. gallick, gabriel lopez-berestein, elsa r. flores, anil k. sood, suyun huang, dihua yu, liuqing yang*, chunru lin*, a jak2-binding long noncoding rna promotes breast cancer brain metastasis. journal of clinical investigation. 2017 dec;127(12):4498-4515. (11) chunlai li#, shouyu wang#, zhen xing, aifu lin, ke liang, jian song, qingsong hu, jun yao, zhongyuan chen, peter k. park, david h. hawke, jianwei zhou, yan zhou, shuxing zhang, han liang, mien-chie hung, gary e. gallick, leng han, chunru lin* and liuqing yang*, a ror1-her3-lncrna signalling axis modulates the hippo-yap pathway to regulate bone metastasis. nature cell biology. 2017 feb;19(2):106-119. (1) 国家自然科学基金面上项目(no. 82273157),2023/01-2026/12 (2) 国家自然科学基金面上项目(no. 82073114),2021/01-2024/12 (3) 国家自然科学基金面上项目(no. 81773383),2018/01-2021/12 (4) 国家自然科学基金面上项目(no. 81370078),2014/01-2017/12 (5) 江苏省杰出青年基金(no. bk20170047),2017/06-2020/12 1、江苏省杰出青年基金(2017 年); 2、江苏省“333 工程”高层次人才培养对象(2016 年); 3、江苏省高校“青蓝工程”中青年骨干教师(2016 年); 4、教育部高等学校自然科学奖二等奖(2013 年,排名第2); 5、中国环境诱变剂学会三致专委会杰出青年奖(2020 年); 6、国际毒理学会青年学者奖(2009 年); |