 吴江
电话：邮箱：wujiang@nju.edu.cn 地址：研究方向：
环境污染与健康、生殖与发育 教育和工作简历： 2012年12月–至今，南京大学，医学院，副教授，硕士生导师 2009年8月–2010年8月，美国university of california at riverside, 访问学者 2009年9月获南京大学内科学博士学位 教学： 先后承担《生理学》、《疾病研究的生物学方法》、《炎症与疾病》、《病原生物学》、《医学寄生虫学》、《生殖生物学》等多门本科/研究生课程；“十二五”普通高等教育本科国家级规划教材，科学出版社《生理学》第四版编委。 1 xiaoyan li, xin zhuang, tianchi xu, min mao, cong wang, yabing chen, xiaodong han*, jiang wu*. expression analysis of micrornas and mrnas in ovarian granulosa cells after microcystin-lr exposure. toxicon. 2017, 129:11-19. doi: 10.1016/j.toxicon.2017.01.022. 2 jie ding, jing wang, haibo jin, tian xia, yi cheng, jiang wu*, xiaodong han*. microcystin-lr reduces the synthesis of gonadotropin-releasing hormone by activating multiple signaling pathways resulting in decrease of testosterone in mice. science of the total environment. 2018, 643:496-506. doi: 10.1016/j.scitotenv.2018.06.123. 3 ling chen, jiwei hou, xiao fu, xiang chen, jiang wu*, xiaodong han*. tpa promotes the proliferation of lung fibroblasts and activates the wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis. cell cycle. 2019 nov;18(22):3137-3146. doi: 10.1080/15384101.2019.1669997. 4 xiaoyan li1, jinling zhu1, jie tian, dongmei li, xiaodong han*, jiang wu*. mc-lr induced overproduction of progesterone via inhibiting mir 5 jinling zhu1, kunyang liu1, ligang pei, xinyue hu, yuchen cai, jie ding, dongmei li, xiaodong han*, jiang wu*. the mechanisms of mitochondrial dysfunction and glucose intake decrease induced by microcystin-lr in ovarian granulosa cells. ecotoxicology and environmental safety. 2021 apr 1;212:111931. doi: 10.1016/j.ecoenv.2021.111931. 6 kunyang liu1, xiaonan zhao1, meihong guo, jinling zhu, dongmei li, jie ding, xiaodong han*, jiang wu*. microcystin-leucine arginine (mc-lr) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cgas-sting signaling. toxicol lett. 2022 jan 12;s0378-4274(22)00014-5. doi: 10.1016/j.toxlet.2022.01.003. 7 meihong guo1, lei yang1, xiaonan zhao, pinru yan, mengjiao zhu, weidong ding, dongmei li, xiaodong han*, jiang wu*. microcystin-lr inhibits early pregnancy by impairing the vascular network of luteum: involvement of the mek/erk/sp1/vegfr2 axis. food chem toxicol. 2022 oct 4;113454. doi: 10.1016/j.fct.2022.113454. 1、国家自然科学基金面上项目：微囊藻毒素-lr诱导雌性小鼠卵巢颗粒细胞凋亡、卵泡闭锁加速的机制研究（31670519） 2、国家自然科学基金青年项目：微囊藻毒素-lr长时期低剂量暴露对雌性小鼠生殖功能的影响及其机制研究（31200401）2019年南京大学医学院优秀教师 |